Low LDL-C Levels and Cancer
نویسندگان
چکیده
منابع مشابه
Implication of Low HDL-c Levels in Patients with Average LDL-c Levels: A Focus on Oxidized LDL, Large HDL Subpopulation, and Adiponectin
To evaluate the impact of low levels of high density lipoprotein cholesterol (HDL-c) on patients with LDL-c average levels, focusing on oxidative, lipidic, and inflammatory profiles. Patients with cardiovascular risk factors (n = 169) and control subjects (n = 73) were divided into 2 subgroups, one of normal HDL-c and the other of low HDL-c levels. The following data was analyzed: BP, BMI, wais...
متن کاملHigh levels of LDL-C combined with low levels of HDL-C further increase platelet activation in hypercholesterolemic patients
High levels of low-density lipoprotein cholesterol (LDL-C) enhance platelet activation, whereas high levels of high-density lipoprotein cholesterol (HDL-C) exert a cardioprotective effect. However, the effects on platelet activation of high levels of LDL-C combined with low levels of HDL-C (HLC) have not yet been reported. We aimed to evaluate the platelet activation marker of HLC patients and ...
متن کاملVery low LDL‐C levels may safely provide additional clinical cardiovascular benefit: the evidence to date
BACKGROUND Cardiovascular disease (CVD) is the leading cause of death in Europe and increased low-density lipoprotein cholesterol (LDL-C) is a major contributor to CVD risk. Extensive evidence from clinical studies of statins has demonstrated a linear relationship between LDL-C levels and CVD risk. It has been proposed that lower LDL-C levels than those currently recommended may provide additio...
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In their trial, Cannon et al. report the superiority of the anti-PCSK9 monoclonal antibody (mAb) alirocumab (SAR236553/REGN727; s.c. 75 mg every 2 weeks) over ezetimibe (oral 10 mg once a day) in the reduction of LDL-cholesterol (LDL-C) levels among 720 patients athigh cardiovascular risk whowere inadequately controlled despite maximally tolerated statin dosage. At week 24, mean reduction in LD...
متن کاملAssociation between LDL-C, Non HDL-C, and Apolipoprotein B Levels with Coronary Plaque Regression
BACKGROUND Previous reports have inferred a linear relationship between LDL-C and changes in coronary plaque volume (CPV) measured by intravascular ultrasound. However, these publications included a small number of studies and did not explore other lipid markers. OBJECTIVE To assess the association between changes in lipid markers and regression of CPV using published data. METHODS We colle...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2008
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2008.08.001